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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FER
All Species:
14.55
Human Site:
S451
Identified Species:
29.09
UniProt:
P16591
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16591
NP_005237.2
822
94638
S451
L
S
D
M
I
S
I
S
E
K
P
L
A
E
Q
Chimpanzee
Pan troglodytes
XP_517863
822
94653
S451
L
S
D
M
I
S
I
S
E
K
P
L
A
E
Q
Rhesus Macaque
Macaca mulatta
XP_001099988
808
93284
S451
L
S
D
M
I
S
I
S
E
K
P
L
A
E
Q
Dog
Lupus familis
XP_851836
820
93016
V449
P
L
Q
L
I
P
E
V
Q
K
P
L
H
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70451
823
94560
V451
Q
V
C
D
V
I
S
V
G
E
R
P
L
A
E
Rat
Rattus norvegicus
P09760
323
37086
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512215
821
94492
S450
F
L
E
V
I
P
T
S
E
K
P
L
P
E
Q
Chicken
Gallus gallus
P00523
533
59991
N198
F
D
N
A
K
G
L
N
V
K
H
Y
K
I
R
Frog
Xenopus laevis
P13116
532
59718
N197
Y
D
A
S
R
G
L
N
V
K
H
Y
K
I
R
Zebra Danio
Brachydanio rerio
XP_693576
842
96630
P458
V
S
F
F
D
V
I
P
T
S
E
K
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18106
1325
150245
T951
A
A
S
I
S
L
S
T
N
R
P
L
Y
E
E
Honey Bee
Apis mellifera
XP_623692
782
90822
V431
V
L
P
R
E
E
V
V
R
L
L
V
T
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
95.1
51.4
N.A.
92.9
36.2
N.A.
88.6
24.9
25.1
73.5
N.A.
28
40
N.A.
N.A.
Protein Similarity:
100
99.8
96.7
70
N.A.
96.8
37.9
N.A.
95.1
38.6
39.5
85.3
N.A.
43.4
61.3
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
0
0
N.A.
53.3
6.6
6.6
13.3
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
20
0
N.A.
66.6
33.3
26.6
20
N.A.
53.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
9
0
0
0
0
0
0
0
0
25
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
25
9
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
9
9
0
34
9
9
0
0
59
17
% E
% Phe:
17
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
0
0
17
0
9
0
0
% H
% Ile:
0
0
0
9
42
9
34
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
59
0
9
17
0
0
% K
% Leu:
25
25
0
9
0
9
17
0
0
9
9
50
9
9
0
% L
% Met:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
17
9
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
0
17
0
9
0
0
50
9
17
0
0
% P
% Gln:
9
0
9
0
0
0
0
0
9
0
0
0
0
0
42
% Q
% Arg:
0
0
0
9
9
0
0
0
9
9
9
0
0
0
17
% R
% Ser:
0
34
9
9
9
25
17
34
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
9
9
0
0
0
9
0
0
% T
% Val:
17
9
0
9
9
9
9
25
17
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _